| / English Dictionary |
KARYOTYPE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
The appearance of the chromosomal makeup of a somatic cell in an individual or species (including the number and arrangement and size and structure of the chromosomes)
Classified under:
Hypernyms ("karyotype" is a kind of...):
composition; constitution; make-up; makeup; physical composition (the way in which someone or something is composed)
II. (verb)
Sense 1
Present simple (first person singular and plural, second person singular and plural, third person plural) of the verb karyotype
Context examples:
Most complete moles (>90%) have a 46,XX karyotype and the rest 46,XY karyotype.
(Complete Hydatidiform Mole, NLM, Medical Subject Headings)
Karyotype with at least three chromosomal aberrations.
(Complex Karyotype, NCI Thesaurus)
These leukemias may have normal karyotypes or additional chromosomal aberrations.
(Acute Myeloid Leukemia with Gene Mutations, NCI Thesaurus)
Information from provider and not independently verified by NIH: Cells are positive for cell markers SSEA-3, SSEA-4, Oct-4, alkaline phosphatase activity and telomerase activity; Cells are negative for the cell marker SSEA-1; Cell has normal karyotype (46 XX); Differentiation in vitro into neuron; Cells were cultured in feeder-free culture condition using Matrigel coated plate.
(MB02, NCI Thesaurus)
Cytogenetics Shared Resource provides Cancer Center members with support in following areas: routine cytogenetic (such as giemsa (G)-banding on fibroblast, lymphoblast or somatic cell hybrid lines to determine karyotypes, etc.), fluorescence in situ hybridization (FISH) for clarification of karyotypes, and SKY (spectral karyotyping), to analyze chromosomal changes, microsatellite analysis of tumors for loss of heterozygosity, mutation analysis of tumors, chimerism studies of bone marrow transplants; maintenance of cell lines and lymphocytes.
(Cytogenetics Shared Resource, NCI Thesaurus)
Cases with normal karyotype have a favorable prognosis.
(Acute Myeloid Leukemia with Mutated CEBPA, NCI Thesaurus)
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