| / English Dictionary |
LIPOSOME
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
An artificially made microscopic vesicle into which nucleic acids can be packaged; used in molecular biology as a transducing vector
Classified under:
Hypernyms ("liposome" is a kind of...):
cyst; vesicle (a small anatomically normal sac or bladderlike structure (especially one containing fluid))
Context examples:
A myristoylated phosphatidylcholine, and a synthetic phospholipid used in liposomes and lipid bilayers with drug delivery property.
(Dimyristoyl Lecithin, NCI Thesaurus)
Upon administration, DOTAP:chol-Fus1 liposome complex accumulates mainly in the lungs and particularly in cancer cells.
(DOTAP:Cholesterol-Fus1 Liposome Complex, NCI Thesaurus)
DOTAP:cholesterol liposome is composed of cationic lipid dioleoyl-trimethylammonium propane (DOTAP) and cholesterol at molar ratio of 1:1.
(C-VISA BikDD:Liposome, NCI Thesaurus)
A cationic liposome preparation of paclitaxel with antineoplastic activity.
(Cationic Liposome-Encapsulated Paclitaxel, NCI Thesaurus)
Also called cytarabine liposome and liposomal cytarabine.
(Depo-Cyt, NCI Dictionary)
After subcutaneous injection of the autologous tumor cell proteoliposomes chronic lymphocytic leukemia vaccine, liposomes deliver the encapsulated tumor antigens into the cytosol of antigen presenting cells (APCs).
(Autologous Tumor Cell Proteoliposome Chronic Lymphocytic Leukemia Vaccine, NCI Thesaurus)
Conjugation of GSH to the PEG molecules directs the liposomes to the GSH transporters on the blood brain barrier (BBB) and improves the delivery of doxorubicin into the brain.
(Glutathione Pegylated Liposomal Doxorubicin Hydrochloride Formulation 2B3-101, NCI Thesaurus)
Liposome encapsulation improves the efficacy and increases the half-life of OSI-7904.
(OSI-7904L, NCI Thesaurus)
Encasement in liposomes improves cisplatin's tumor bioavailability and toxicity profile.
(Cisplatin Liposomal, NCI Thesaurus)
A liposomal formulation consisting of short-interfering RNAs (siRNAs) directed against ephrin type-A receptor 2 (EphA2) and encapsulated into 1,2-dioleoyl-sn-glycero-3-phosphatidylcholine (DOPC) neutral liposomes, with potential antineoplastic activity.
(EphA2-targeting DOPC-encapsulated siRNA, NCI Thesaurus)
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