LOCALIZATION

Pronunciation (US): (GB):

I. (noun)

Sense 1

Meaning:

A determination of the place where something is

Example:

he got a good fix on the target

Synonyms:

fix; localisation; localization; locating; location

Classified under:

Nouns denoting acts or actions

Hypernyms ("localization" is a kind of...):

determination; finding (the act of determining the properties of something, usually by research or calculation)

Hyponyms (each of the following is a kind of "localization"):

echo sounding; echolocation (determining the location of something by measuring the time it takes for an echo to return from it)

Derivation:

localize (locate)

localize (identify the location or place of)

Sense 2

Meaning:

(physiology) the principle that specific functions have relatively circumscribed locations in some particular part or organ of the body

Synonyms:

localisation; localisation of function; localisation principle; localization; localization of function; localization principle

Classified under:

Nouns denoting cognitive processes and contents

Hypernyms ("localization" is a kind of...):

principle; rule (a rule or law concerning a natural phenomenon or the function of a complex system)

Domain category:

physiology (the branch of the biological sciences dealing with the functioning of organisms)

Hyponyms (each of the following is a kind of "localization"):

lateralisation; laterality; lateralization (localization of function on either the right or left sides of the brain)

Credits

Context examples:

NAG has 2 clusters of nuclear localization signals, one in the N-terminus of the longer variant and the other in the common C-terminus.

(Neuroblastoma-Amplified Sequence, NCI Thesaurus)

This allele, which encodes myomegalin protein, is involved in the localization of phosphodiesterase activity.

(PDE4DIP wt Allele, NCI Thesaurus)

This gene may play a role in signal transduction, sugar transport and protein localization.

(PEA15 Gene, NCI Thesaurus)

This allele, which encodes astrocytic phosphoprotein PEA-15 protein, may be involved in the modulation of signaling, transport of carbohydrates and protein localization.

(PEA15 wt Allele, NCI Thesaurus)

The neomycin phosphotransferase gene product has no direct therapeutic value; it serves as a molecular marker to monitor the presence and localization of the PG13/Lnc8-transduced T-lymphocytes in the host.

(PG13/LNc8 Retroviral Transduced Cloned T-Cells, NCI Thesaurus)

This gene plays a role in protein complex localization.

(PDE4DIP Gene, NCI Thesaurus)

The Nurf301 subunit contains a bromodomain transcription factor domain, a zinc finger binding domain, nuclear localization signals, and motifs associated with rapid protein degradation.

(NURF, NCI Thesaurus)

This allele, which encodes merlin protein, plays a role in the mediation of protein localization, cytoskeletal conformation and ion transport.

(NF2 wt Allele, NCI Thesaurus)

Treatment with FK506, a specific calcineurin inhibitor, prevents nuclear localization of NF-ATc4.

(NFAT Pathway, NCI Thesaurus/BIOCARTA)

This protein is involved in centrosome localization.