| / English Dictionary |
LU
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A trivalent metallic element of the rare earth group; usually occurs in association with yttrium
Synonyms:
atomic number 71; Lu; lutecium; lutetium
Classified under:
Hypernyms ("Lu" is a kind of...):
metal; metallic element (any of several chemical elements that are usually shiny solids that conduct heat or electricity and can be formed into sheets etc.)
Context examples:
Lu-177 MoAb CC49 delivers gamma radiation emitting Lu-177 nuclide directly to tumor cells that express TAG-72, and so may be used in radioimmunotherapeutic treatment of cancers.
(Lutetium Lu 177 Monoclonal Antibody CC49, NCI Thesaurus)
A radioimmunoconjugate, which consists of a monoclonal antibody against the cell-surface antigen CD37 covalently linked, via the bifunctional, macrocyclic chelating agent tetra-azacyclododecanetetra-acetic acid (DOTA), to the beta-emitting radioisotope lutetium Lu 177, with potential antineoplastic activity.
(Lutetium Lu 177 DOTA-Tetulomab, NCI Thesaurus)
After pretargeting with a bispecific monoclonal antibody (BiMoAB) directed against both a tumor associated antigen (TAA) and the HSG hapten-peptide, the HSG portion of administered Lu-177-labeled di-HSG-DOTA peptide IMP-288 binds the anti-HSG portion of the BiMoAB; Lu-177 radioisotopic activity localized to tumor cells bearing the TAA can then be visualized scintigraphically.
(Lutetium Lu 177-DOTA-di-HSG Peptide IMP-288, NCI Thesaurus)
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