LUPUS

Pronunciation (US): (GB):

I. (noun)

Sense 1

Meaning:

A constellation in the southern hemisphere near Centaurus

Classified under:

Nouns denoting natural objects (not man-made)

Instance hypernyms:

constellation (a configuration of stars as seen from the earth)

Sense 2

Meaning:

Any of several forms of ulcerative skin disease

Classified under:

Nouns denoting stable states of affairs

Hypernyms ("lupus" is a kind of...):

disease of the skin; skin disease; skin disorder (a disease affecting the skin)

Hyponyms (each of the following is a kind of "lupus"):

lupus vulgaris (tuberculosis of the skin; appears first on the face and heals slowly leaving deep scars)

discoid lupus erythematosus; DLE (a chronic skin disease occurring primarily in women between the ages of 20 and 40; characterized by an eruption of red lesions over the cheeks and bridge of the nose)

LE; lupus erythematosus (a chronic inflammatory collagen disease affecting connective tissue (skin or joints))

disseminated lupus erythematosus; SLE; systemic lupus erythematosus (an inflammatory disease of connective tissue with variable features including fever and weakness and fatigability and joint pains and skin lesions on the face or neck or arms)

Credits

Context examples:

Patients with this disorder may also have a thymoma (a tumor of the thymus) or an autoimmune condition such as lupus erythematosus or rheumatoid arthritis.

(Acquired pure red cell aplasia, NCI Dictionary)

The study has implications not just for people with psoriasis, but for those with other chronic inflammatory diseases, such as lupus and rheumatoid arthritis.

(Psoriasis therapy linked to reduced coronary inflammation in patients with the skin condition, National Institutes of Health)

Mutation of the gene is associated with systemic lupus erythematosus type 2.

(PDCD1 wt Allele, NCI Thesaurus)

Many of the regulatory genes that contribute to lupus and other autoimmune disorders did not interact with EBNA2, and some individuals with activated regulatory genes associated with disease risk do not develop disease.

(Epstein-Barr virus protein can “switch on” risk genes for autoimmune diseases, National Institutes of Health)

A form of lupus erythematosus in which the skin may be the only organ involved or in which skin involvement precedes the spread into other body systems.

(Cutaneous Lupus Erythematosus, NLM, Medical Subject Headings)

The mothers of the affected babies may be asymptomatic or suffer from systemic lupus erythematosus, Sjogren's syndrome, or rheumatoid arthritis.

(Neonatal Lupus Erythematosus, NCI Thesaurus)

Mutation of the gene is associated with systemic lupus erythematosus type 9.

(CR2 wt Allele, NCI Thesaurus)

Certain allelic variants of the NAT2 gene are associated with systemic lupus erythematosus and certain types of cancer such as bladder cancer and colorectal cancer.

(NAT2 wt Allele, NCI Thesaurus)

It can result from an acute post-infectious glomerulonephritis, membranoproliferative glomerulonephritis or lupus glomerulonephritis.

(Nephrotic Syndrome with Lesion of Hypocomplementemic Glomerulonephritis, NCI Thesaurus)

A reaction to a drug characterized by skin findings common to lupus including photosensitivity and butterfly rash; typically it resolves after drug discontinuation.