| / English Dictionary |
LYMPHOCYTE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
An agranulocytic leukocyte that normally makes up a quarter of the white blood cell count but increases in the presence of infection
Synonyms:
Classified under:
Hypernyms ("lymphocyte" is a kind of...):
leucocyte; leukocyte; WBC; white blood cell; white blood corpuscle; white cell; white corpuscle (blood cells that engulf and digest bacteria and fungi; an important part of the body's defense system)
Hyponyms (each of the following is a kind of "lymphocyte"):
B cell; B lymphocyte (a lymphocyte derived from bone marrow that provides humoral immunity; it recognizes free antigen molecules in solution and matures into plasma cells that secrete immunoglobulin (antibodies) that inactivate the antigens)
T cell; T lymphocyte (a small lymphocyte developed in the thymus; it orchestrates the immune system's response to infected or malignant cells)
lymphoblast (an immature lymphocyte)
plasma cell; plasmacyte (a cell that develops from a B lymphocyte in reaction to a specific antigen; found in bone marrow and sometimes in the blood)
Holonyms ("lymphocyte" is a part of...):
lymphatic system; systema lymphaticum (the interconnected system of spaces and vessels between body tissues and organs by which lymph circulates throughout the body)
Derivation:
lymphocytic (of or relating to lymphocytes)
Context examples:
HIV infects white blood cells known as T lymphocytes, particularly the CD4+ T cells that recognise infection and gets the immune system to respond.
(HIV seeks refuge in immune cells to avoid full elimination, SciDev.Net)
A recombinant monoclonal antibody directed against the human suppressor-cytotoxic T-cell subset and designed to deplete circulating Leu 2A-positive lymphocytes.
(Monoclonal Antibody hLEU 2A, NCI Thesaurus)
The number of lymphocytes found in a given volume of blood.
(Absolute Blood Lymphocyte Count, NCI Thesaurus)
A mature T-lymphocyte that has encountered its cognate antigen and is primed to reproduce and elicit a stronger immune response upon a second encounter with the antigen.
(Memory T-Lymphocyte, NCI Thesaurus)
A preparation of peripheral blood lymphocytes (PBLs) transduced with a retroviral vector encoding a T cell chimeric antigen receptor (CAR) specific for mesothelin with potential immunostimulatory and antineoplastic activities.
(Mesothelin-specific Chimeric Antigen Receptor-engineered Peripheral Blood Lymphocytes, NCI Thesaurus)
Upon administration, Melan-A VLP vaccine may activate the immune system to exert a specific cytotoxic T lymphocyte (CTL) response against cancer cells expressing the Melan A antigen, resulting in tumor cell lysis.
(Melan-A VLP Vaccine, NCI Thesaurus)
Upon administration, monoclonal antibody HuAFP31 (mAb HuAFP31) binds to and stimulates a cytotoxic T lymphocyte (CTL) response against tumor cells that express alpha fetoprotein.
(Monoclonal Antibody HuAFP31, NCI Thesaurus)
Melanoma theraccine may induce a rise in the level of cytotoxic T-lymphocyte precursors.
(Melanoma Theraccine, NCI Thesaurus)
Upon administration, mesothelioma tumor lysate-pulsed autologous dendritic cell vaccine may stimulate the host immune system to mount a specific cytotoxic T lymphocyte (CTL) response against mesothelioma tumor cells, resulting in tumor cell lysis.
(Mesothelioma Tumor Lysate-Pulsed Autologous Dendritic Cell Vaccine, NCI Thesaurus)
The immunological function of MHC Class-II proteins is to bind and present antigenic peptides on the surfaces of cells for recognition by the antigen-specific T cell receptors of lymphocytes.
(MHC Class II Protein, NCI Thesaurus)
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