LYSIS

Pronunciation (US): (GB):

Irregular inflected form: lyses

I. (noun)

Sense 1

Meaning:

(biochemistry) dissolution or destruction of cells such as blood cells or bacteria

Classified under:

Nouns denoting natural processes

Hypernyms ("lysis" is a kind of...):

disintegration; dissolution (separation into component parts)

Domain category:

biochemistry (the organic chemistry of compounds and processes occurring in organisms; the effort to understand biology within the context of chemistry)

Hyponyms (each of the following is a kind of "lysis"):

autolysis; self-digestion (lysis of plant or animal tissue by an internal process)

bacteriolysis (dissolution or destruction of bacteria)

cytolysis (pathological breakdown of cells by the destruction of their outer membrane)

haematolysis; haemolysis; hematolysis; hemolysis (lysis of erythrocytes with the release of hemoglobin)

karyolysis (disintegration and dissolution of a cell nucleus when a cell dies)

necrolysis (disintegration and dissolution of dead tissue)

osteolysis (lysis of bone caused by disease or infection or inadequate blood supply)

radiolysis (molecular disintegration resulting from radiation)

thrombolysis (the process of breaking up and dissolving blood clots)

Sense 2

Meaning:

Recuperation in which the symptoms of an acute disease gradually subside

Classified under:

Nouns denoting natural processes

Hypernyms ("lysis" is a kind of...):

convalescence; recovery; recuperation (gradual healing (through rest) after sickness or injury)

Credits

Context examples:

This results in cytotoxic T lymphocyte (CTL) and antibody responses against CD20-expressing tumor cells, causing tumor cell lysis.

(Anti-CD20-CAR-CD3zeta-4-1BB-expressing Autologous T-lymphocyte Cells, NCI Thesaurus)

Anti-AGS-8 monoclonal antibody AGS-8M4 selectively binds to AGS-8, triggering complement-dependent cell lysis and antibody-dependent cell-mediated cytotoxicity in tumor cells expressing AGS-8.

(Anti-AGS-8 Monoclonal Antibody AGS-8M4, NCI Thesaurus)

This results in cell lysis and prevents viral replication and the development of CMV disease.

(Multi-peptide CMV-Modified Vaccinia Ankara Vaccine, NCI Thesaurus)

Vaccination with NY-ESO-1 peptide vaccine may stimulate the host immune system to mount a humoral and cytotoxic T lymphocyte (CTL) response to cells expressing NY-ESO-1 antigen, resulting in tumor cell lysis.

(NY-ESO-1 Peptide Vaccine, NCI Thesaurus)

Upon intratumoral administration, the adenovirus selectively infects and replicates in tumor cells, which may result in tumor cell lysis.

(Adenovirus-mediated Human Interleukin-12, NCI Thesaurus)

Vaccination with the neoantigen-based melanoma vaccine stimulates the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing the neoantigens, which results in tumor cell lysis.

(Neoantigen-based Melanoma-Poly-ICLC Vaccine, NCI Thesaurus)

This agent selectively binds to CD52, thereby triggering a host immune response that results in lysis of CD52 + cells.

(Alemtuzumab, NCI Thesaurus)

This results in cell lysis and inhibition of cancer cell proliferation.

(Allogeneic Epstein-Barr Virus-Specific Cytotoxic T-Lymphocytes, NCI Thesaurus)

This leads to GBM cell lysis.

(Allogeneic Glioblastoma Stem-like Cell Line Lysate-pulsed Autologous Dendritic Cell Vaccine, NCI Thesaurus)

Upon administration, AFP peptide-pulsed autologous dendritic cell vaccine may stimulate anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against AFP-expressing cancer cells, resulting in tumor cell lysis.