| / English Dictionary |
LYSOSOME
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
An organelle found in the cytoplasm of most cells (especially in leukocytes and liver and kidney cells)
Classified under:
Hypernyms ("lysosome" is a kind of...):
cell organ; cell organelle; organelle (a specialized part of a cell; analogous to an organ)
Context examples:
Beta 2 adrenergic receptor (413 aa, 47 kD) is a cell communication protein that is encoded by the human ADRB2 gene and has roles in endosome to lysosome transport and signal transduction.
(Beta-2-Adrenergic Receptor, NCI Thesaurus)
This nanosensor is the first to noninvasively detect fat in the lysosomes of the Kupffer cells, potentially identifying those most at risk of progressing.
(High-Fat, High-Sugar Diet Causes Lasting Harmful Effects on Liver, The Titi Tudorancea Bulletin)
An organelle formed by the fusion of a phagosome with the lysosome, where the contents of the phagosome are degraded.
(Phagolysosome, NCI Thesaurus)
The chaperone restored the enzyme’s ability to gain entry into lysosomes—the cell compartment where fatty materials are broken down—and increased enzyme activity.
(Molecule may impact Gaucher, Parkinson’s disease, NIH)
This maturation of phagosomes involves regulated interaction with the other membrane organelles, including recycling endosomes, late endosomes and lysosomes.
(Phagocytosis Pathway, NCI Thesaurus/KEGG)
Monoubiquitination of cell-surface receptors serves as a signal to target them to lysosome, where they are degraded by lysosomal proteases.
(Monoubiquitination, NCI Thesaurus)
Although the exact mechanism remains to be elucidated, mefloquine, a weak base, preferentially accumulates in lysosomes and disrupts lysosomal function and integrity, thereby leading to host cell death.
(Mefloquine, NCI Thesaurus)
LLME undergoes a condensation process catalyzed by dipeptidyl peptidase I (DPPI) in lysosomes.
(L-Leucyl-L-Leucine Methyl Ester, NCI Thesaurus)
A lipid bilayer that encloses a lysosome.
(Membrane of the Lysosome, NCI Thesaurus)
A membrane bound cytoplasmic compartment that drives molecular traffic between the plasma membrane and lysosome.
(Endosome, NCI Thesaurus)
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