| / English Dictionary |
MACROPHAGE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A large phagocyte; some are fixed and other circulate in the blood stream
Classified under:
Hypernyms ("macrophage" is a kind of...):
phagocyte; scavenger cell (a cell that engulfs and digests debris and invading microorganisms)
Hyponyms (each of the following is a kind of "macrophage"):
histiocyte (a macrophage that is found in connective tissue)
Context examples:
Macrophages may be present in the alveolar lumens.
(Alveoli Epithelial Hyperplasia of the Mouse Pulmonary System, NCI Thesaurus/MMHCC)
Monocytes are a class of phagocytes involved in non-specific immune defense that develop into macrophages.
(Monocyte Phagocytosis and Adhesion Pathway, NCI Thesaurus/BIOCARTA)
A fully human monoclonal antibody against RON (recepteur d'origine nantais; macrophage stimulating 1 receptor), with potential antineoplastic activity.
(Narnatumab, NCI Thesaurus)
This allele, which encodes macrophage mannose receptor 1 protein, plays a role in mediating endocytosis of glycoproteins by macrophages.
(MRC1 wt Allele, NCI Thesaurus)
Inflammation is induced by release of vasodilatory, opsonizing, and chemotactic mediators that attract phagocytizing macrophages and leukocytes; dilate local blood vessels, increasing local blood flow and capillary permeability; and induce pain.
(Negative Regulation of Inflammatory Response Process, NCI Thesaurus)
A type of immune cell that is made in the bone marrow and travels through the blood to tissues in the body where it becomes a macrophage.
(Monocyte, NCI Dictionary)
This results in the suppression of recruitment and activation of tumor associated macrophages (TAM) within the tumor microenvironment.
(Anti-c-fms Monoclonal Antibody AMG 820, NCI Thesaurus)
The anti-inflammatory effects of this agent appear to be related to the inhibition of nitric oxide (NO) production by macrophages.
(Andrographolide, NCI Thesaurus)
A recombinant fusion protein derived from the coding sequences of two growth factors, interleukin-3 (IL-3) and granulocyte-macrophage colony-stimulating factor (GM-CSF).
(Milodistim, NCI Thesaurus)
As an immunomodulator, miltefosine stimulates T-cells, macrophages and the expression of interleukin 3 (IL-3), granulocyte-macrophage colony stimulating factor (GM-CSF), and interferon gamma (INF-gamma).
(Miltefosine, NCI Thesaurus)
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