MANIPULATION

Pronunciation (US): (GB):

I. (noun)

Sense 1

Meaning:

The action of touching with the hands (or the skillful use of the hands) or by the use of mechanical means

Synonyms:

handling; manipulation

Classified under:

Nouns denoting acts or actions

Hypernyms ("manipulation" is a kind of...):

touch; touching (the act of putting two things together with no space between them)

Hyponyms (each of the following is a kind of "manipulation"):

fielding ((baseball) handling the ball while playing in the field)

Derivation:

manipulate (treat manually, as with massage, for therapeutic purposed)

manipulate (hold something in one's hands and move it)

Sense 2

Meaning:

Exerting shrewd or devious influence especially for one's own advantage

Example:

his manipulation of his friends was scandalous

Synonyms:

manipulation; use

Classified under:

Nouns denoting acts or actions

Hypernyms ("manipulation" is a kind of...):

influence (causing something without any direct or apparent effort)

Hyponyms (each of the following is a kind of "manipulation"):

mind game (deliberate actions of calculated psychological manipulation intended to intimidate or confuse (usually for competitive advantage))

Derivation:

manipulate (maintain influence over (others or oneself) skillfully, usually to one's advantage)

manipulate (influence or control shrewdly or deviously)

Credits

Context examples:

The methods and tools used for DNA analysis and manipulation.

(Molecular Genetic Technique, NCI Thesaurus)

Technique or procedure for manipulation of cells and analysis of cell properties and subcellular features.

(Cytological Procedure, NCI Thesaurus)

The manipulation of stem cell culture conditions to induce differentiation into a particular cell type.

(Directed differentiation, The Titi Tudorancea Bulletin)

In mice, genetic manipulations of this gene had effects opposite from those expected if HDL-C were protective.

(When HDL cholesterol doesn’t protect against heart disease, NIH)

This gene regulates the apoptotic pathway by manipulation of the cell cycle.

(BIRC5 Gene, NCI Thesaurus)

However, aged cells tend to be highly resistant to any type of manipulation intended to induce regeneration.

(Scientists Discover Molecule that Could Reverse Cellular Aging, The Titi Tudorancea Bulletin)

With genetic manipulation, the scientists prevented Tfh13 cell development in mice and found that the animals did not make anaphylactic IgE to allergens.

(Scientists discover immune cell subtype in mice that drives allergic reactions, National Institutes of Health)

Bleeding that is induced by gentle manipulation of the gingival tissue at the depth of the gingival sulcus.

(Bleeding on Probing, NCI Thesaurus)

Cancer cells often generate energy through glycolytic fermentation more than oxidative phosphorylation, suggesting that manipulation of metabolism may provide a therapeutic strategy.

(Glycolysis Pathway, NCI Thesaurus/BIOCARTA)

The computer simulation of chemical structures or processes; allows for the exploration, visualization, and manipulation of molecular structures and properties.