| / English Dictionary |
MONOCLONAL ANTIBODY
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
Any of a class of antibodies produced in the laboratory by a single clone of cells or a cell line and consisting of identical antibody molecules
Synonyms:
monoclonal; monoclonal antibody
Classified under:
Hypernyms ("monoclonal antibody" is a kind of...):
antibody (any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response)
Hyponyms (each of the following is a kind of "monoclonal antibody"):
infliximab; Remicade (a monoclonal antibody (trade name Remicade) used to treat Crohn's disease and rheumatoid arthritis; administered by infusion; use and dosage must be determined by a physician)
Context examples:
There are many kinds of monoclonal antibodies.
(Monoclonal antibody, NCI Dictionary)
A murine monoclonal antibody directed against the ganglioside GD2 with potential antineoplastic activity.
(Monoclonal Antibody 14G2A, NCI Thesaurus)
A nonspecific monoclonal antibody Fab fragment for murine leukemia virus (MuLV) 1.4.
(Monoclonal Antibody 1.4 F(ab), NCI Thesaurus)
A murine monoclonal antibody directed against CD20, a cross-membrane ion channel phosphoprotein expressed by B cells, with potential antineoplastic activity.
(Monoclonal Antibody 1F5, NCI Thesaurus)
A humanized monoclonal antibody directed against human CD74 with potential antineoplastic activity.
(Milatuzumab, NCI Thesaurus)
A melanoma monoclonal antibody, subclass IgG2A, may have potential use as a diagnostic agent and, therapeutically, may induce macrophage-mediated cytotoxicity against antibody-bound melanoma cells.
(Melanoma Monoclonal Antibody hIgG2A, NCI Thesaurus)
An immunoconjugate consisting of milatuzumab, a humanized monoclonal antibody against CD74, conjugated to the anthracycline antibiotic doxorubicin with potential antineoplastic activity.
(Milatuzumab-Doxorubicin Antibody-Drug Conjugate, NCI Thesaurus)
A humanized monoclonal antibody directed against interleukin-13 (IL-13) with anti-asthmatic and anti-inflammatory activities.
(Anrukinzumab, NCI Thesaurus)
ZMapp is composed of 3 different monoclonal antibodies (mAbs).
(Experimental Ebola antibody protects monkeys, NIH)
A humanized monoclonal antibody directed against C-C chemokine receptor 4 (CCR4) with potential anti-inflammatory and antineoplastic activities.
(Mogamulizumab, NCI Thesaurus)
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