| / English Dictionary |
NALOXONE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A potent narcotic antagonist (trade name Narcan) especially effective with morphine
Synonyms:
Classified under:
Nouns denoting man-made objects
Hypernyms ("naloxone" is a kind of...):
narcotic antagonist (an antagonist used to counteract the effects of narcotics (especially to counteract the depression of respiration))
Context examples:
Naloxone reverses the effects of opioid analgesics by binding to the opioid receptors in the CNS, and inhibiting the typical actions of opioid analgesics, including analgesia, euphoria, sedation, respiratory depression, miosis, bradycardia, and physical dependence.
(Naloxone, NCI Thesaurus)
A prolonged-release tablet formulation composed of the hydrochloride salt form of the opioid receptor agonist oxycodone and the hydrochloride salt form of the opioid receptor antagonist naloxone which may produce analgesia while relieving opioid-mediated gastrointestinal (GI) side effects.
(Oxycodone Hydrochloride/Naloxone Hydrochloride Prolonged-release Tablet, NCI Thesaurus)
Importantly, data from the meditation plus naloxone group showed that naloxone did not block meditation’s pain-relieving effects.
(Scientists discover non-opioid pain pathway in the brain, NIH)
Researchers recorded pain reports in 78 healthy adults during meditation or a non-meditation control in response to painful heat stimuli and intravenous administration of the opioid antagonist naloxone (a drug that blocks the transmission of opioid activity) or placebo saline.
(Scientists discover non-opioid pain pathway in the brain, NIH)
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