| / English Dictionary |
NEURAL TUBE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A tube of ectodermal tissue in the embryo from which the brain and spinal cord develop
Classified under:
Hypernyms ("neural tube" is a kind of...):
ectoblast; ectoderm; exoderm (the outer germ layer that develops into skin and nervous tissue)
Context examples:
A congenital defect characterized by failure of the neural tube to close completely; this results in the presence of openings in the brain or spinal cord.
(Neural Tube Defect, NCI Thesaurus)
Mutation of the gene is associated with both folate-sensitive neural tube defects and methylcobalamin deficiency type E.
(MTRR wt Allele, NCI Thesaurus)
Neural crest cells become the peripheral nervous system while the neural tube forms the central nervous system.
(Nervous System Development, NCI Thesaurus)
Folate, an essential B vitamin, reduces the fetus’ risk for neural tube defects, which are malformations affecting the brain, spine and spinal cord.
(Proper maternal folate level may reduce child obesity risk, NIH)
Some birth defects like cleft lip or neural tube defects are structural problems that can be easy to see.
(Birth Defects, Centers for Disease Control and Prevention)
Mutation of the gene is associated with both methylcobalamin deficiency type G and susceptibility to folate-sensitive neural tube defects.
(MTR wt Allele, NCI Thesaurus)
Allelic variants of the MTHFR gene are associated with susceptibility to numerous disorders including acute leukemia, colon cancer, neural tube defects and occlusive vascular disease.
(MTHFR wt Allele, NCI Thesaurus)
Inhibitory signals that block heart formation in anterior paraxial mesoderm include Wnt family members expressed in dorsal neural tube and anti-BMPs expressed in the axial tissues (i.e., noggin in the notochord).
(ALK Pathway, NCI Thesaurus/BIOCARTA)
The main features of this syndrome involve retinal abnormalities and this protein may play an important role in retinal structure and in neural tube closure.
(Collagen XVIII (Alpha 1), NCI Thesaurus)
This allele, which encodes collagen alpha-1 (XVIII) chain protein, plays a role in the development of both the neural tube and the retina.
(COL18A1 wt Allele, NCI Thesaurus)
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