| / English Dictionary |
ONCOGENE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A gene that disposes normal cells to change into cancerous tumor cells
Synonyms:
Classified under:
Hypernyms ("oncogene" is a kind of...):
cistron; factor; gene ((genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity)
Context examples:
This allele, which encodes Myb proto-oncogene protein, plays a role in both the modulation of transcription by RNA polymerase II and differentiation of hematopoietic progenitor cells.
(MYB wt Allele, NCI Thesaurus)
Myc proto-oncogene protein (439 aa, ~49 kDa) is encoded by the human MYC gene.
(Myc Proto-Oncogene Protein, NCI Thesaurus)
NMYC interactor (NMI) is a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif.
(NMYC Interactor, NCI Thesaurus/LocusLink)
Oncogenes may cause the growth of cancer cells.
(Oncogene, NCI Dictionary)
Human v-abl Abelson murine leukemia viral oncogene homolog 1 (ABL1) gene, located at 9q34.1, encodes proto-oncogene tyrosine-protein kinase ABL1 protein.
(Oncogene ABL1, NCI Thesaurus)
Any DNA sequence alteration process occurring in a proto-oncogene, resulting in loss of regulation of the gene product, and predisposing the cell to neoplastic transformation.
(Oncogene Activation Process, NCI Thesaurus)
Recombination of the wild-type allele with the RET proto-oncogene wild-type allele is found in papillary thyroid carcinomas.
(NCOA4 wt Allele, NCI Thesaurus)
N-myc proto-oncogene protein (464 aa, ~50 kDa) is encoded by the human MYCN gene.
(N-Myc Proto-Oncogene Protein, NCI Thesaurus)
This allele, which encodes myc proto-oncogene protein, plays a role in the regulation of transcription by RNA polymerase II.
(MYC wt Allele, NCI Thesaurus)
This allele, which encodes L-myc-1 proto-oncogene protein, is involved in modulation of transcription by RNA polymerase II.
(MYCL1 wt Allele, NCI Thesaurus)
YOU MAY ALSO LIKE
