| / English Dictionary |
OSTEOBLAST
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A cell from which bone develops
Synonyms:
Classified under:
Hypernyms ("osteoblast" is a kind of...):
embryonic cell; formative cell (a cell of an embryo)
Context examples:
This gene plays a role in bone formation via regulation of osteoblast differentiation.
(BMP2 Gene, NCI Thesaurus)
Osteoblasts and stromal cells may react to bone metastases by producing M-CSF and its osteoclastogenic cofactor RANKL (receptor activator of NF-kappaB ligand).
(Anti-M-CSF Monoclonal Antibody MCS110, NCI Thesaurus)
Mature osteoblasts that have become embedded in the bone matrix.
(Osteocyte, NLM, Medical Subject Headings)
In addition, fluoride is a mitogen for osteoblasts and stimulates bone formation.
(Fluoride Ion, NCI Thesaurus)
The skeleton participates in pH homeostasis as a buffering organ and osteoblasts respond to pH changes in the physiologic range.
(G Protein-Coupled Receptor 68, NCI Thesaurus)
This gene plays a role in osteoblast differentiation and ossification.
(DMP1 Gene, NCI Thesaurus)
RANK-ligand and osteoprotegerin are produced by osteoblasts and some factors regulate osteoclast activity indirectly through their action on the expression of these factors by osteoblasts.
(Bone Remodeling Pathway, NCI Thesaurus/BIOCARTA)
Osteoblasts mineralize bone matrix by promoting hydroxyapatite crystal formation and growth in the interior of membrane-limited matrix vesicles (MVs) and by propagating the crystals onto the collagenous extracellular matrix.
(Bone Mineralization Regulation Pathway, NCI Thesaurus/BIOCARTA)
Upon administration of calcium-46 chloride aqueous solution, calcium-46 is preferentially taken up by osteoblasts, which generate mineralized osteoid containing calcium.
(Calcium-46 Chloride Aqueous Solution, NCI Thesaurus)
Upon administration of calcium-41 chloride aqueous solution, calcium-41 is preferentially taken up by osteoblasts, which generate mineralized osteoid containing calcium.
(Calcium-41 Chloride Aqueous Solution, NCI Thesaurus)
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