| / English Dictionary |
PHASE II
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A clinical trial on more persons than in phase I; intended to evaluate the efficacy of a treatment for the condition it is intended to treat; possible side effects are monitored
Synonyms:
phase II; phase II clinical trial
Classified under:
Nouns denoting acts or actions
Hypernyms ("phase II" is a kind of...):
clinical test; clinical trial (a rigorously controlled test of a new drug or a new invasive medical device on human subjects; in the United States it is conducted under the direction of the FDA before being made available for general clinical use)
Context examples:
Design, identification, synthesis, extraction, purification, modification, or characterization of potential anticancer agents; studies of their metabolism, distribution, excretion, physiological effects, molecular interactions, structural analysis, toxicity, mechanism of action, antitumor effects in vivo (nonhuman species) or in vitro (human or nonhuman), and phase I and phase II clinical trials.
(Drug Development, NCI Thesaurus)
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