| / English Dictionary |
PHOSPHOPROTEIN
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
Containing chemically bound phosphoric acid
Classified under:
Hypernyms ("phosphoprotein" is a kind of...):
protein (any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes)
Hyponyms (each of the following is a kind of "phosphoprotein"):
casein (a milk protein used in making e.g. plastics and adhesives)
Context examples:
CD20 is a non-glycosylated cell surface phosphoprotein that is exclusively expressed on B cells during most stages of B cell development.
(Ocaratuzumab, NCI Thesaurus)
Phosducin, encoded by the PDC gene, is a phosphoprotein that is located in the outer and inner segments of the rod cells in the retina.
(Phosducin, NCI Thesaurus/LocusLink)
This protein plays a role in signaling and as both a dual-specificity phosphoprotein phosphatase and a lipid phosphatase.
(Phosphatidylinositol-3,4,5-Trisphosphate 3-Phosphatase and Dual-Specificity Protein Phosphatase PTEN, NCI Thesaurus)
Encoded by Protein Phosphatase Genes, Protein Phosphatase enzymes remove tyrosine-, serine-, or threonine-bound phosphate groups from many phosphoproteins, including enzymes phosphorylated by a tyrosine kinase or a serine/threonine kinase.
(Phosphoprotein Phosphatase, NCI Thesaurus)
This allele, which encodes astrocytic phosphoprotein PEA-15 protein, may be involved in the modulation of signaling, transport of carbohydrates and protein localization.
(PEA15 wt Allele, NCI Thesaurus)
STMN1, a ubiquitous cytosolic phosphoprotein and tubulin modulator that plays a key role in mitosis, is overexpressed in a variety of tumors and correlates with poor prognosis.
(pbi-shRNA STMN1 Lipoplex, NCI Thesaurus)
ETS1 encodes 42-52 kD nuclear phosphoprotein transcription factors that interact with purine-rich promoter/enhancer sequences in the TCRA gene.
(Oncogene ETS, NCI Thesaurus)
HDM2, a zinc finger nuclear phosphoprotein, is a negative regulator of the p53 pathway, often overexpressed in cancer cells and has been implicated in cancer cell proliferation and survival.
(p53/HDM2 Interaction Inhibitor CGM097, NCI Thesaurus)
This allele, which encodes phosphoprotein associated with glycosphingolipid-enriched microdomains 1, is involved in T cell receptor signal transduction repression.
(PAG1 wt Allele, NCI Thesaurus)
This allele, which encodes carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2, plays a role in the hydrolysis of phosphoproteins.
(CTDSP2 wt Allele, NCI Thesaurus)
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