| / English Dictionary |
PLAQUE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A memorial made of brass
Synonyms:
brass; memorial tablet; plaque
Classified under:
Nouns denoting man-made objects
Hypernyms ("plaque" is a kind of...):
memorial; monument (a structure erected to commemorate persons or events)
Sense 2
Meaning:
(pathology) a small abnormal patch on or inside the body
Classified under:
Hypernyms ("plaque" is a kind of...):
dapple; fleck; maculation; patch; speckle; spot (a small contrasting part of something)
Domain category:
pathology (the branch of medical science that studies the causes and nature and effects of diseases)
Hyponyms (each of the following is a kind of "plaque"):
amyloid plaque; amyloid protein plaque (a plaque consisting of tangles of amyloid protein in nervous tissue (a pathological mark of Alzheimer's disease))
arterial plaque (a fatty deposit inside an arterial wall; characteristic of atherosclerosis)
bacterial plaque; dental plaque (a film of mucus and bacteria deposited on the teeth that encourages the development of dental caries)
II. (verb)
Sense 1
Present simple (first person singular and plural, second person singular and plural, third person plural) of the verb plaque
Context examples:
In Alzheimer’s disease, beta-amyloid clumps together to form amyloid plaques, negatively impacting communication between neurons.
(Lack of sleep may be linked to risk factor for Alzheimer’s disease, National Institutes of Health)
A novel statin that induces plaque regression and elevates HDL-cholesterol levels.
(Pitavastatin, NCI Thesaurus)
This damage could initiate events leading to atherosclerosis (build-up of plaque), which can restrict blood flow over time.
(Bone-Like Particles Found Travelling through Human Bloodstream, The Titi Tudorancea Bulletin)
A calcium salt formulation of pitavastatin, a novel statin that induces plaque regression and elevates HDL-cholesterol levels.
(Pitavastatin Calcium, NCI Thesaurus)
Excessive beta-amyloids may clump together to create plaques, which disrupt neurons and result in symptoms that are associated with the illness.
(Alzheimer's Disease Gene Successfully Removed From Human Brain, The Titi Tudorancea Bulletin)
One of the major hallmarks of Alzheimer’s disease is amyloid plaques that are found in between nerve cells.
(Alzheimer’s protein may have natural antibiotic role, NIH)
Prior research had linked psoriasis with premature development of high-risk coronary plaque.
(Study links psoriasis treatment and improvement in heart artery disease, The Titi Tudorancea Bulletin)
Plaques may also be a build-up of substances from a fluid, such as cholesterol in the blood vessels.
(Plaque, NCI Dictionary)
If the arteries are very narrow, you may need an operation called an endarterectomy to remove the plaque.
(Carotid Artery Disease, NIH)
The amyloid-beta peptide (Ab), a proteolytic fragment of amyloid precursor protein (APP), is the major component of senile plaques, the hallmark of Alzheimer's disease.
(Platelet Amyloid Precursor Protein Pathway, NCI Thesaurus/BIOCARTA)
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