| / English Dictionary |
POLYPEPTIDE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A peptide containing 10 to more than 100 amino acids
Classified under:
Hypernyms ("polypeptide" is a kind of...):
peptide (amide combining the amino group of one amino acid with the carboxyl group of another; usually obtained by partial hydrolysis of protein)
Holonyms ("polypeptide" is a substance of...):
protein (any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes)
Context examples:
Neurofilament medium polypeptide (916 aa, ~102 kDa) is encoded by the human NEFM gene.
(Neurofilament Medium Polypeptide, NCI Thesaurus)
Neurofilament, heavy polypeptide (1026 aa, ~112 kDa) is encoded by the human NEFH gene.
(Neurofilament Heavy Polypeptide, NCI Thesaurus)
Family of polypeptide growth factors produced by peripheral target tissues as well as the nervous system, which are critical to neuronal growth, regeneration, survival, and differentiation.
(Neurotrophic Factor, NCI Thesaurus)
They are transported to the plasma membrane as cleaved, but otherwise intact polypeptides.
(Notch Signaling Pathway, NCI Thesaurus/KEGG)
The repair of damaged DNA involves at least 30 polypeptides within two different sub-pathways of NER known as transcription-coupled repair (TCR-NER) and global genome repair (GGR-NER).
(Nucleotide Excision Repair Pathway, NCI Thesaurus/KEGG)
A recombinant single-chain polypeptide engineered to exhibit the full binding and activity of an anti-CD37 monoclonal antibody with potential immunostimulatory and antineoplastic activities.
(Otlertuzumab, NCI Thesaurus)
CD3 zeta is one of several membrane-bound polypeptides found in the TCR/CD3 complex, which regulates both the assembly of complete TCR complexes and their expression on the cell surface.
(Anti-CD19-CAR Retroviral Vector-Transduced Autologous T Cells, NCI Thesaurus)
The sequence of amino acids along a polypeptide chain.
(Amino acid sequence, NCI Thesaurus)
It has also been argued that the gamma secretase is not presenilin-1 itself, but another polypeptide that requires Notch for its activity and is distinct from Presenilin-1.
(Notch Proteolysis and Signaling Pathway, NCI Thesaurus/BIOCARTA)
A single chain polypeptide isolated from bovine lung with antifibrinolytic and anti-inflammatory activities.
(Aprotinin, NCI Thesaurus)
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