| / English Dictionary |
PROGESTIN
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
Any of a group of steroid hormones that have the effect of progesterone
Synonyms:
Classified under:
Hypernyms ("progestin" is a kind of...):
sex hormone; steroid; steroid hormone (any hormone affecting the development and growth of sex organs)
Hyponyms (each of the following is a kind of "progestin"):
Lipo-Lutin; progesterone (a steroid hormone (trade name Lipo-Lutin) produced in the ovary; prepares and maintains the uterus for pregnancy)
megestrol; megestrol acetate (a synthetic progestational compound used to treat endometrial carcinoma)
norethandrolone; norethindrone; norethindrone acetate; Norlutin (a synthetic progestational hormone (trade name Norlutin) used in oral contraceptives and to treat endometriosis)
norethynodrel (a progesterone derivative used in oral contraceptives and in the control of menstruation and the treatment of abnormal uterine bleeding)
norgestrel (synthetic progestin used in oral contraceptives)
medroxyprogesterone; Provera (a progestin compound (trade name Provera) used to treat menstrual disorders)
Context examples:
This allele, which encodes cytochrome P450 17A1 protein, plays a role in the synthesis of progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens.
(CYP17A1 wt Allele, NCI Thesaurus)
Because chronic estrogen stimulation unopposed by progesterone may increase the risk of the endometrial carcinoma, administration of a combination estrogen-progestin in postmenopause may reduce the risk for women who require estrogen replacement therapy.
(Estradiol/Norethindrone Acetate Tablet, NCI Thesaurus)
A dermal patch that contains estrogen and progestin hormones for release and absorption through the skin and into the body to prevent pregnancy.
(Contraceptive Patch, NCI Thesaurus)
The progestin effect on the cervical mucus also reduces the penetrability of sperm.
(Intrauterine device, NCI Thesaurus)
Most oral contraceptives include estrogen and progestin.
(Oral contraceptive pill, NCI Dictionary)
The orally bioavailable acetate salt of norethindrone, a synthetic progestin with some anabolic, estrogenic, and androgenic activities.
(Norethindrone Acetate, NCI Thesaurus)
A synthetic spironolactone analogue and progestin with progestational and anti-mineralocorticoid activity.
(Drospirenone, NCI Thesaurus)
As a do all progestins, medroxyprogesterone binds to and activates nuclear receptors which subsequently bind to and activate target genes for transcription.
(Medroxyprogesterone, NCI Thesaurus)
Localized to the endoplasmic reticulum (ER), the cytochrome P450 enzyme CYP17 (P450C17 or CYP17A1) exhibits both 17alpha-hydroxylase and 17,20-lyase activities, and plays a key role in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens.
(Galeterone, NCI Thesaurus)
The cytochrome P450 enzyme CYP17A1 (P450C17), localized to the endoplasmic reticulum (ER), exhibits both 17alpha-hydroxylase and 17,20-lyase activities, and plays a key role in the steroidogenic pathway that produces steroidal hormones, such as progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens.
(Orteronel, NCI Thesaurus)
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