| / English Dictionary |
PROINFLAMMATORY
| Pronunciation (US): |  | (GB): | |
I. (adjective)
Sense 1
Meaning:
Tending to cause inflammation
Synonyms:
pro-inflammatory; proinflammatory
Classified under:
Similar:
unhealthy (not in or exhibiting good health in body or mind)
Context examples:
By complexing with and trapping NFKB in the cytoplasm, unphosphorylated NFKBIA inhibits NFKB target gene transcription in cell adhesion, immune and proinflammatory responses, apoptosis, differentiation, and growth.
(I Kappa B-Alpha Protein, NCI Thesaurus)
This leads to the release of proinflammatory cytokines and stimulates an innate immune response against vaccine antigens.
(Lipopolysaccharide, NCI Thesaurus)
This gene is involved in the modulation of proinflammatory gene expression.
(MYD88 Gene, NCI Thesaurus)
Proinflammatory cytokine produced primarily by T-lymphocytes or their precursors.
(Interleukin-17, NLM, Medical Subject Headings)
This allele, which encodes myeloid differentiation primary response protein MyD88, plays a role in both protein-protein interactions and the regulation of the expression of proinflammatory genes.
(MYD88 wt Allele, NCI Thesaurus)
The inflammasomes are critical for generating mature proinflammatory cytokines in concert with Toll-like receptor signaling pathway.
(NOD-Like Receptor Signaling Pathway, NCI Thesaurus/KEGG)
Methylprednisolone binds to and activates specific nuclear receptors, resulting in altered gene expression and inhibition of proinflammatory cytokine production.
(Methylprednisolone, NCI Thesaurus)
In addition, this agent may reduce the secretion of proinflammatory cytokines and may potentiate natural and acquired immunity.
(Lactobacillus plantarum 299v/Lactobacillus acidophilus/Bifidobacterium lactis Probiotic Supplement, NCI Thesaurus)
As a result, proinflammatory cytokine production such as IL-1, IL-2 and IL-6 is down-regulated and cytotoxic T-lymphocyte activation is inhibited.
(Methylprednisolone Acetate, NCI Thesaurus)
Darglitazone may be able to abrogate acute cerebral inflammatory responses via its suppression of proinflammatory gene expression.
(Darglitazone, NCI Thesaurus)
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