| / English Dictionary |
PROSTAGLANDIN
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A potent substance that acts like a hormone and is found in many bodily tissues (and especially in semen); produced in response to trauma and may affect blood pressure and metabolism and smooth muscle activity
Classified under:
Hypernyms ("prostaglandin" is a kind of...):
autacoid; autocoid (any physiologically active internal secretion especially one of uncertain classification)
Context examples:
Nafazatrom, originally developed as an antithrombotic agent, inhibits the key prostaglandin catabolic enzyme, 15-hydroxyprostaglandin dehydrogenase, which prolongs the biological half-life of prostacyclin (prostaglandin I2; PGI2) and prevents intravascular coagulation.
(Nafazatrom, NCI Thesaurus)
The resulting decrease in prostaglandin synthesis is responsible for the therapeutic effects of naproxen.
(Naproxen, NCI Thesaurus)
The resulting decrease in prostaglandin synthesis is responsible for the therapeutic effects of nabumetone.
(Nabumetone, NCI Thesaurus)
The naturally occuring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions.
(Alprostadil, NCI Thesaurus)
Compounds such as rosiglitazone (Rosi) and prostaglandin E2 analog (PGE2) have been shown to have browning effects on white fat tissue—increasing metabolism and the growth of new blood vessels.
(Nanoparticles target, transform fat tissue, NIH)
The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of mefenamic acid.
(Mefenamic Acid, NCI Thesaurus)
Glucosamine inhibits interleukin-1-induced production of inflammatory mediators (nitric oxide, prostaglandin E2), and inhibit aggrecanase activity, which results in preservation of proteoglycan and chondrocytes.
(MSM/Glucosamine, NCI Thesaurus)
Nedocromil inhibits the activation and release of inflammatory mediators (leukotrienes, histamine and prostaglandins) from a variety of cells involved in hypersensitivity reactions, including mast cells, eosinophils, neutrophils, macrophages, monocytes and platelets.
(Nedocromil Calcium, NCI Thesaurus)
Acetaminophen exerts analgesic and antipyretic actions by inhibiting prostaglandin synthesis.
(Nyquil, NCI Thesaurus)
Oxtriphylline appears to inhibit phosphodiesterase and prostaglandin production, regulates calcium flux and intracellular calcium distribution, and antagonizes adenosine.
(Oxtriphylline, NCI Thesaurus)
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