| / English Dictionary |
PROTEASE INHIBITOR
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
An antiviral drug used against HIV; interrupts HIV replication by binding and blocking HIV protease; often used in combination with other drugs
Synonyms:
Classified under:
Nouns denoting man-made objects
Hypernyms ("protease inhibitor" is a kind of...):
antiviral; antiviral agent; antiviral drug (any drug that destroys viruses)
Hyponyms (each of the following is a kind of "protease inhibitor"):
Crixivan; indinavir (a protease inhibitor (trade name Crixivan) used for treating HIV)
nelfinavir; Viracept (a protease inhibitor (trade name Viracept) used in treating HIV usually in combination with other drugs)
Norvir; ritonavir (a protease inhibitor (trade name Norvir) used in treating HIV)
Invirase; saquinavir (a weak protease inhibitor (trade name Invirase) used in treating HIV)
Holonyms ("protease inhibitor" is a part of...):
drug cocktail; HAART; highly active antiretroviral therapy (a combination of protease inhibitors taken with reverse transcriptase inhibitors; used in treating AIDS and HIV)
Context examples:
Lopinavir/ritonavir is a type of anti-HIV agent and a type of protease inhibitor.
(Lopinavir/ritonavir, NCI Dictionary)
One Kallikrein Inhibitor Unit is identical to the quantity of protease inhibitor (eg, aprotinin) that has the ability to inhibit two kallikrein units by 50% under optimal conditions.
(Kallikrein Inhibitor Unit, NCI Thesaurus)
As an inhibitor of the cytochrome P450 system, delavirdine may result in increased serum levels of co-administered protease inhibitors metabolized by the cytochrome P450 system.
(Delavirdine, NCI Thesaurus)
Encoded by human APP Gene (APP Family), Amyloid Beta A4 Protein Precursor is an N-/O-glycosylated sulfated metal ion-binding type I cell surface protein containing a BPTI protease inhibitor domain.
(Amyloid Beta A4 Protein Precursor, NCI Thesaurus)
This protein has activity as a protease inhibitor.
(Alpha-2-Macroglobulin, NCI Thesaurus)
This allele, which encodes alpha-2-macroglobulin protein, plays a role in various processes as a protease inhibitor.
(A2M wt Allele, NCI Thesaurus)
A member of the serpin family of serine protease inhibitor proteins that inhibits plasminogen activator type proteases.
(Plasminogen Activator Inhibitor, NCI Thesaurus)
An extract of soybeans enriched in Bowman-Birk inhibitor (BBI), a soybean-derived, 71-amino acid, polypeptide and serine protease inhibitor with potential chemopreventive activity.
(Bowman-Birk inhibitor concentrate, NCI Thesaurus)
This gene has activity as a protease inhibitor.
(A2M Gene, NCI Thesaurus)
Plasma serine protease inhibitor (406 aa, ~46 kDa) is encoded by the human SERPINA5 gene.
(Plasma Serine Protease Inhibitor, NCI Thesaurus)
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