| / English Dictionary |
REPLICATION
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
The act of making copies
Example:
Gutenberg's reproduction of holy texts was far more efficient
Synonyms:
replication; reproduction
Classified under:
Nouns denoting acts or actions
Hypernyms ("replication" is a kind of...):
copying (an act of copying)
Hyponyms (each of the following is a kind of "replication"):
scanning (the act of systematically moving a finely focused beam of light or electrons over a surface in order to produce an image of it for analysis or transmission)
sound reproduction (the reproduction of sound)
Sense 2
Meaning:
The repetition of an experiment in order to test the validity of its conclusion
Example:
scientists will not believe an experimental result until they have seen at least one replication
Classified under:
Nouns denoting acts or actions
Hypernyms ("replication" is a kind of...):
repeating; repetition (the act of doing or performing again)
Derivation:
replicate (make or do or perform again)
Sense 3
Meaning:
Copy that is not the original; something that has been copied
Synonyms:
replica; replication; reproduction
Classified under:
Nouns denoting man-made objects
Hypernyms ("replication" is a kind of...):
copy (a thing made to be similar or identical to another thing)
Hyponyms (each of the following is a kind of "replication"):
toy (a nonfunctional replica of something else (frequently used as a modifier))
Sense 4
Meaning:
The repetition of a sound resulting from reflection of the sound waves
Example:
she could hear echoes of her own footsteps
Synonyms:
echo; replication; reverberation; sound reflection
Classified under:
Nouns denoting attributes of people and objects
Hypernyms ("replication" is a kind of...):
reflection; reflectivity; reflexion (the ability to reflect beams or rays)
Hyponyms (each of the following is a kind of "replication"):
re-echo (the echo of an echo)
Sense 5
Meaning:
(law) a pleading made by a plaintiff in reply to the defendant's plea or answer
Classified under:
Nouns denoting communicative processes and contents
Hypernyms ("replication" is a kind of...):
pleading ((law) a statement in legal and logical form stating something on behalf of a party to a legal proceeding)
Domain category:
jurisprudence; law (the collection of rules imposed by authority)
Sense 6
Meaning:
A quick reply to a question or remark (especially a witty or critical one)
Example:
it brought a sharp rejoinder from the teacher
Synonyms:
comeback; counter; rejoinder; replication; retort; return; riposte
Classified under:
Nouns denoting communicative processes and contents
Hypernyms ("replication" is a kind of...):
reply; response (the speech act of continuing a conversational exchange)
Hyponyms (each of the following is a kind of "replication"):
back talk; backtalk; lip; mouth; sass; sassing (an impudent or insolent rejoinder)
Sense 7
Meaning:
(genetics) the process whereby DNA makes a copy of itself before cell division
Classified under:
Nouns denoting natural processes
Hypernyms ("replication" is a kind of...):
biological process; organic process (a process occurring in living organisms)
Domain category:
genetic science; genetics (the branch of biology that studies heredity and variation in organisms)
Derivation:
replicate (reproduce or make an exact copy of)
Context examples:
The analogue's structure differs only slightly from CTP's — but the difference is sufficient to bring viral replication to a halt.
(Scientists Discover How Antiviral Gene Works, The Titi Tudorancea Bulletin)
The scientists compared patterns of modifications in chromatin that are needed for the cell to access the DNA inside, and the changes in DNA replication patterns as a result of these modifications.
(Expanding Our Understanding of Genomics, NIH)
Merbarone interferes with DNA replication via binding directly to topoisomerase II at a domain that maybe shared by other topoisomerase II cleavage-enhancing agents, ex., etoposide.
(Merbarone, NCI Thesaurus)
This agent is also incorporated into DNA in the form of deoxythioguanosine, which results in the disruption of DNA replication.
(Mercaptopurine, NCI Thesaurus)
These mutations are associated with decreased fidelity of DNA replication.
(Microsatellite Mutator Phenotype, NCI Thesaurus)
N,N-Dibenzyl Daunomycin interacts with topoisomerase II, thereby inhibiting DNA replication and repair and promoting DNA fragmentation.
(N,N-Dibenzyl Daunomycin, NCI Thesaurus)
Metamelfalan causes crosslinking of DNA, thereby preventing DNA replication and eventually cellular proliferation.
(Metamelfalan, NCI Thesaurus)
Includes infection, replication, and expression of the viral genome.
(Molecular Virology, NCI Thesaurus)
Used to induce cancer in experimental animal models, N-ethyl-N'-nitro-N-nitrosoguanidine ethylates DNA, resulting in single- and double-stranded DNA breaks and the inhibition of DNA replication.
(N-ethyl-N'-nitro-N-nitrosoguanidine, NCI Thesaurus)
This inhibits the religation of topoisomerase I-mediated single-stranded DNA breaks and produces potentially lethal double-stranded DNA breaks when encountered by the DNA replication machinery, resulting in the inhibition of DNA replication and apoptosis.
(Mureletecan, NCI Thesaurus)
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