/ English Dictionary

SCHIZOPHRENIA

Pronunciation (US):

(GB):

 I. (noun) 

Sense 1

Meaning:

Any of several psychotic disorders characterized by distortions of reality and disturbances of thought and language and withdrawal from social contact

Synonyms:

dementia praecox; schizophrenia; schizophrenic disorder; schizophrenic psychosis

Classified under:

Nouns denoting stable states of affairs

Hypernyms ("schizophrenia" is a kind of...):

psychosis (any severe mental disorder in which contact with reality is lost or highly distorted)

Hyponyms (each of the following is a kind of "schizophrenia"):

borderline schizophrenia; latent schizophrenia (schizophrenia characterized by mild symptoms or by some preexisting tendency to schizophrenia)

catatonia; catatonic schizophrenia; catatonic type schizophrenia (a form of schizophrenia characterized by a tendency to remain in a fixed stuporous state for long periods; the catatonia may give way to short periods of extreme excitement)

disorganized schizophrenia; disorganized type schizophrenia; hebephrenia; hebephrenic schizophrenia (a form of schizophrenia characterized by severe disintegration of personality including erratic speech and childish mannerisms and bizarre behavior; usually becomes evident during puberty; the most common diagnostic category in mental institutions)

paranoic type schizophrenia; paranoid schizophrenia; paraphrenia; paraphrenic schizophrenia (a form of schizophrenia characterized by delusions (of persecution or grandeur or jealousy); symptoms may include anger and anxiety and aloofness and doubts about gender identity; unlike other types of schizophrenia the patients are usually presentable and (if delusions are not acted on) may function in an apparently normal manner)

acute schizophrenic episode; reactive schizophrenia (schizophrenia of abrupt onset and relatively short duration (a few weeks or months))

Derivation:

schizophrenic (suffering from some form of schizophrenia)

schizophrenic (of or relating to or characteristic of schizophrenia)

Credits

 Context examples: 

Researchers have identified both common and rare genetic variations that contribute to risk for schizophrenia.

(Schizophrenia risk gene linked to cognitive deficits in mice, National Institutes of Health)

Inherited PLA2G4C polymorphisms are associated with susceptibility to schizophrenia.

(PLA2G4C wt Allele, NCI Thesaurus)

Disturbances affecting the neurotransmitter dopamine are associated with a host of mental and neurological disorders, such as schizophrenia and Parkinson’s disease.

(Neuromelanin-sensitive MRI identified as a potential biomarker for psychosis, National Institutes of Health)

This prevents the actions of dopamine, thereby reducing the hallucinations and delusions that are associated with schizophrenia.

(Fluphenazine, NCI Thesaurus)

A type of schizophrenia characterized by abnormality of motor behavior which may involve particular forms of stupor, rigidity, excitement or inappropriate posture.

(Catatonic Type Schizophrenia, NLM, Medical Subject Headings)

Copy number variation for the gene is associated with schizophrenia and autism.

(ASTN2 wt Allele, NCI Thesaurus)

In addition, the study identified 153 significant genes, and found that major depression shared six loci that are also associated with schizophrenia.

(Forty-Four Genomic Variants Linked to Major Depression, The Titi Tudorancea Bulletin)

Translocations may lead to medical problems such as leukemia, breast cancer, schizophrenia, muscular dystrophy, and Down syndrome.

(Chromosomal Translocation Process, NCI Dictionary)

Defects in the COMT gene are associated with susceptibility to neurological disorders such as schizophrenia and bipolar disorder.

(COMT wt Allele, NCI Thesaurus)

Decreased DLG4 gene expression is associated with bipolar disorder and schizophrenia.

(DLG4 wt Allele, NCI Thesaurus)

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