| / English Dictionary |
SEGREGATION
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
The act of segregating or sequestering
Example:
sequestration of the jury
Synonyms:
segregation; sequestration
Classified under:
Nouns denoting acts or actions
Hypernyms ("segregation" is a kind of...):
separation (the social act of separating or parting company)
Antonym:
integration (the action of incorporating a racial or religious group into a community)
Derivation:
segregate (separate or isolate (one thing) from another and place in a group apart from others)
segregate (divide from the main body or mass and collect)
segregationist (someone who believes the racial groups should be kept apart)
Sense 2
Meaning:
A social system that provides separate facilities for minority groups
Synonyms:
segregation; separatism
Classified under:
Nouns denoting groupings of people or objects
Hypernyms ("segregation" is a kind of...):
social organisation; social organization; social structure; social system; structure (the people in a society considered as a system organized by a characteristic pattern of relationships)
Hyponyms (each of the following is a kind of "segregation"):
racial segregation (segregation by race)
de facto segregation (segregation (especially in schools) that happens in fact although not required by law)
de jure segregation (segregation that is imposed by law)
purdah; sex segregation (the traditional Hindu or Muslim system of keeping women secluded)
white separatism (a social system in which white people live separately from members of other races)
Derivation:
segregate (separate by race or religion; practice a policy of racial segregation)
segregationist (someone who believes the racial groups should be kept apart)
Sense 3
Meaning:
(genetics) the separation of paired alleles during meiosis so that members of each pair of alleles appear in different gametes
Classified under:
Nouns denoting natural processes
Hypernyms ("segregation" is a kind of...):
biological process; organic process (a process occurring in living organisms)
Domain category:
genetic science; genetics (the branch of biology that studies heredity and variation in organisms)
Holonyms ("segregation" is a part of...):
meiosis; miosis; reduction division ((genetics) cell division that produces reproductive cells in sexually reproducing organisms; the nucleus divides into four nuclei each containing half the chromosome number (leading to gametes in animals and spores in plants))
Context examples:
Alisertib binds to and inhibits Aurora A kinase, which may result in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and inhibition of cell proliferation.
(Alisertib, NCI Thesaurus)
This allele, which encodes serine/threonine-protein kinase 12, plays a role in chromosome segregation modulation during cellular mitosis and meiosis.
(AURKB wt Allele, NCI Thesaurus)
This protein is involved in mediating microtubular structure and facilitating chromosome segregation during mitosis and meiosis.
(Aurora Kinase A, NCI Thesaurus)
This protein plays a role in both the modulation of microtubule structure and facilitation of chromosome segregation during mitosis and meiosis.
(Aurora Kinase B, NCI Thesaurus)
During mitosis, chromatin is condensed for segregation of chromosomes, while for transcription chromatin is more open.
(AKAP8 in Mitosis Pathway, NCI Thesaurus/BIOCARTA)
Aurora kinase inhibitor BI 811283 binds to and inhibits Aurora kinases, resulting in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and inhibition of cell proliferation.
(Aurora Kinase Inhibitor BI 811283, NCI Thesaurus)
KSP is an ATP-dependent microtubule motor protein that is essential for the formation of bipolar spindles and the proper segregation of sister chromatids during mitosis.
(KSP Inhibitor ARRY-520, NCI Thesaurus)
The faithful segregation of genetic information requires highly orchestrated changes of chromosome structure during the mitotic cell cycle.
(Mitotic Sister Chromatid Cohesion, NCI Thesaurus)
It is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis.
(MutS Homolog 4, NCI Thesaurus)
APC mutant cells form mitotic spindles with microtubules that ineffectively connect with kinetochores, leading to chromosomal instability and defective chromosome segregation.
(Adenomatous Polyposis Coli Protein, NCI Thesaurus)
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