| / English Dictionary |
SPLICING
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A junction where two things (as paper or film or magnetic tape) have been joined together
Example:
the break was due to an imperfect splice
Synonyms:
splice; splicing
Classified under:
Nouns denoting man-made objects
Hypernyms ("splicing" is a kind of...):
conjunction; junction (something that joins or connects)
Derivation:
splice (join the ends of)
II. (verb)
Sense 1
-ing form of the verb splice
Context examples:
This allele exhibits a clinically-relevant SNP (g.6986A>G) in exon 10 that causes a splicing defect.
(CYP3A5*10 Allele, NCI Thesaurus)
This protein plays a role in the mediation of mRNA splicing and transcriptional regulation.
(Nuclease-Sensitive Element-Binding Protein 1, NCI Thesaurus)
Several LMYC mRNAs are produced in SCCL cells by alternative splicing and alternative polyadenylation.
(Oncogene LMYC, NCI Thesaurus)
The ERBA1 gene at 17q11.2 encodes ERBA alpha-1, ERBA alpha-2, and ERBA alpha-3, each produced by alternative splicing.
(Oncogene ERB A, NCI Thesaurus)
Two isoforms (A, B) are produced by alternative splicing.
(Chemokine-Like Receptor 1, NCI Thesaurus)
Encoded as ten alternate splicing variant isoforms by human BIN1 Gene, ubiquitously expressed nucleocytoplasmic adaptor protein Bridging Integrator 1 exhibits differential binding to dynamin, synaptojanin (via sh3 domain), alpha-adaptin, endophilin, clathrin, and MYC protein.
(Bridging Integrator 1, NCI Thesaurus)
Three isoforms exist from alternative splicing.
(Placental Growth Factor, NCI Thesaurus/LocusLink)
AVPR2 expression has also been described in fetal lung tissue and lung cancer associated with alternative splicing.
(Arginine Vasopressin Receptor 2, NCI Thesaurus/LocusLink)
The splicing factor SF3b is a multiprotein complex integral to the accurate excision of introns from pre-messenger RNA; the subunit SAP130 associates with U2 snRNP and is recruited to prespliceosomal complexes.
(Pladienolide Derivative E7107, NCI Thesaurus)
This protein is involved in both transcriptional regulation and mRNA splicing.
(PC4 and SFRS1-Interacting Protein Isoform 2, NCI Thesaurus)
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