TRANSDUCE

Pronunciation (US): (GB):

I. (verb)

Verb forms

Present simple: I / you / we / they transduce ... he / she / it transduces

Past simple: transduced

Past participle: transduced

-ing form: transducing

Sense 1

Meaning:

Cause transduction (of energy forms)

Classified under:

Verbs of size, temperature change, intensifying, etc.

Hypernyms (to "transduce" is one way to...):

change over; convert (change from one system to another or to a new plan or policy)

Sentence frame:

Something ----s something

Derivation:

transducer (an electrical device that converts one form of energy into another)

transduction (the process whereby a transducer accepts energy in one form and gives back related energy in a different form)

Credits

Context examples:

Cell surface sorting of the signal-transducing APP depends on a cytoplasmic tyrosine-based basolateral sorting signal (BaSS) sequence to which APPBP2 specifically binds.

(Amyloid Beta Precursor Protein-Binding Protein 2, NCI Thesaurus)

Cells specialized to detect and transduce light.

(Murine Photoreceptors, Vertebrate, NLM, Medical Subject Headings)

This local signaling at the terminus or local signaling at the cell body appears distinct from the signaling pathway that transduces the survival signal from the target tissue.

(Neuronal Survival Pathway, NCI Thesaurus/BIOCARTA)

A preparation of peripheral blood lymphocytes (PBLs) transduced with a retroviral vector encoding a T cell chimeric antigen receptor (CAR) specific for mesothelin with potential immunostimulatory and antineoplastic activities.

(Mesothelin-specific Chimeric Antigen Receptor-engineered Peripheral Blood Lymphocytes, NCI Thesaurus)

Transduce signals via at least two pathways, one inhibiting adenylyl cyclase and the other regulating phospholipide metabolism and calcium concentration.

(Melatonin Receptor, NCI Thesaurus)

Upon transfusion, the anti-CD19-CAR FMC63-28Z retroviral vector-transduced allogeneic T lymphocytes specifically recognize and kill CD19-expressing tumor cells.

(Anti-CD19-CAR FMC63-28Z Retroviral Vector-transduced Allogeneic T-lymphocytes, NCI Thesaurus)

Oncogene TIM encodes a predicted 60 kD protein containing a DBL homology domain, shared by several signal transducing regulators of small GTP-binding proteins.

(Oncogene TIM, NCI Thesaurus)

T cells harvested from a patient with adenosine deaminase (ADA) deficiency and transduced with a vector containing the gene for ADA.

(ADA Transduced T Cell, NCI Thesaurus)

Autologous dendritic cells (DCs) transduced with the replication-deficient adenoviral vector Ad5F53 encoding the Epstein-Barr virus (EBV) transmembrane latent membrane proteins 1 and 2 (LMP1/LMP2) with potential immunostimulatory activity.

(Ad5F35-LMP1/LMP2-Transduced Autologous Dendritic Cells, NCI Thesaurus)

Tumor cells adjacent to tumor cells transduced with this agent may be killed through a 'bystander effect'.