| / English Dictionary |
TRNA
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
RNA molecules present in the cell (in at least 20 varieties, each variety capable of combining with a specific amino acid) that attach the correct amino acid to the protein chain that is being synthesized at the ribosome of the cell (according to directions coded in the mRNA)
Synonyms:
acceptor RNA; soluble RNA; transfer RNA; tRNA
Classified under:
Hypernyms ("tRNA" is a kind of...):
ribonucleic acid; RNA ((biochemistry) a long linear polymer of nucleotides found in the nucleus but mainly in the cytoplasm of a cell where it is associated with microsomes; it transmits genetic information from DNA to the cytoplasm and controls certain chemical processes in the cell)
Context examples:
Composed of an alpha subunit nucleotide binding domain and a beta/gamma subunit nucleotide exchange complex, Elongation Factor 1 is responsible for delivery of aminoacyl tRNAs to the ribosome.
(Elongation Factor 1B1, NCI Thesaurus)
This protein is involved in the positive regulation of tRNA binding to the ribosome.
(Elongation Factor 1-Alpha 2, NCI Thesaurus)
This protein plays a role in the modulation of guanine nucleotide exchange to promote the transport of aminoacyl-tRNA to the ribosome.
(Elongation Factor 1-Beta, NCI Thesaurus)
This allele, which encodes angiogenin protein, plays a role in the inhibition of protein synthesis via hydrolysis of cellular tRNAs.
(ANG wt Allele, NCI Thesaurus)
There are 20 families of tRNA, one for each of the amino acids.
(Genes Can be Read in Different Ways, NIH, US)
This allele, which encodes aminoacyl tRNA synthase complex-interacting multifunctional protein 2, is involved in both the modulation of translation and the regulation of ubiquitination.
(AIMP2 wt Allele, NCI Thesaurus)
Borrelidin inhibits translation by binding to 4 sites that are necessary for threonyl-tRNA synthetase to function.
(Scientists Discover Antibiotic Mechanism, NIH)
This allele, which encodes phenylalanyl-tRNA synthetase beta chain protein, plays a role in the mediation of translation through the regulation of the synthesis of amino acid/transfer RNA complexes.
(FARSB wt Allele, NCI Thesaurus)
This agent is also incorporated into RNA, thereby disrupting normal RNA function and impairing tRNA cytosine-5-methyltransferase activity.
(Azacitidine, NCI Thesaurus)
Mupirocin inhibits bacterial protein synthesis by specific reversible binding to bacterial isoleucyl tRNA synthase.
(Mupirocin, NCI Thesaurus)
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