| / English Dictionary |
TYROSINE KINASE INHIBITOR
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A drug used in cases of chronic myeloid leukemia
Classified under:
Nouns denoting man-made objects
Hypernyms ("tyrosine kinase inhibitor" is a kind of...):
medicament; medication; medicinal drug; medicine ((medicine) something that treats or prevents or alleviates the symptoms of disease)
Context examples:
MP470 is a type of tyrosine kinase inhibitor.
(MP470, NCI Dictionary)
A protein tyrosine kinase inhibitor that has specific activity for the epidermal growth factor receptor.
(Compound 32, NCI Thesaurus)
A small molecule and orally available inhibitor of colony-stimulating factor-1 receptor (CSF1R; cFMS) with potential antineoplastic activity. cFMS tyrosine kinase inhibitor ARRY-382 binds to and inhibits the activity of cFMS.
(cFMS Tyrosine Kinase Inhibitor ARRY-382, NCI Thesaurus)
It is a type of receptor tyrosine kinase inhibitor and a type of angiogensis inhibitor.
(ABT-869, NCI Dictionary)
A molecular genetic abnormality in the kinase domain of the BCR-ABL fusion gene that results in resistance to tyrosine kinase inhibitors.
(BCR-ABL TKI-Resistant Mutation, NCI Thesaurus)
It is a type of antiangiogenesis agent and a type of vascular endothelial growth factor (VEGF) receptor tyrosine kinase inhibitor.
(AZD2171, NCI Dictionary)
An orally bioavailable pan-HER tyrosine kinase inhibitor with potential antineoplastic activity.
(pan-HER Kinase Inhibitor AC480, NCI Thesaurus)
An orally bioavailable receptor tyrosine kinase inhibitor.
(Orantinib, NCI Thesaurus)
The hydrochloride salt of nilotinib, an orally bioavailable aminopyrimidine-derivative Bcr-Abl tyrosine kinase inhibitor with antineoplastic activity.
(Nilotinib Hydrochloride Anhydrous, NCI Thesaurus)
A 3-cyanoquinoline pan-ErbB tyrosine kinase inhibitor with potential antineoplastic activity.
(Pelitinib, NCI Thesaurus)
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