| / English Dictionary |
VACCINE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
Immunogen consisting of a suspension of weakened or dead pathogenic cells injected in order to stimulate the production of antibodies
Synonyms:
Classified under:
Nouns denoting man-made objects
Hypernyms ("vaccine" is a kind of...):
immunizing agent; immunogen (any substance or organism that provokes an immune response (produces immunity) when introduced into the body)
Hyponyms (each of the following is a kind of "vaccine"):
DPT vaccine (abbreviation for combination vaccine against diphtheria and pertussis (whooping cough) and tetanus toxoids; usually given in a series of injections in early childhood)
pneumococcal vaccine; Pneumovax (vaccine (trade name Pneumovax) effective against the 23 most common strains of pneumococcus)
poliovirus vaccine (vaccine prepared from poliovirus to provide immunity to poliomyelitis)
proteosome; proteosome vaccine (a form of vaccine that can be administered by an inhaler)
Derivation:
vaccinate (perform vaccinations or produce immunity in by inoculation)
Context examples:
A vaccine containing HER2/Neu-derived epitope (amino acids 776-790) linked to li-Key peptide (li-Key/HER2/neu hybrid peptide or AE37), and combined with granulocyte-macrophage colony-stimulating factor (GM-CSF), with potential antineoplastic and immunoadjuvant activities.
(AE37 Peptide/GM-CSF Vaccine, NCI Thesaurus)
A cancer vaccine composed of naked plasmid DNA of the gene for the tumor-associated antigen alpha-fetoprotein (AFP), a macromolecule that acts as a specific immunologic target for hepatocellular carcinoma.
(AFP Gene Hepatocellular Carcinoma Vaccine, NCI Thesaurus)
A cell-based cancer vaccine composed of autologous dendritic cells (DCs) transduced with a replication-deficient adenovirus vector encoding HER-2 with potential antineoplastic activity.
(Adenovirus HER2-Transduced Autologous Dendritic Cell Vaccine, NCI Thesaurus)
The cytokine GM-CSF enhances the immunogenicity of CA9-based DC vaccines.
(AdGMCAIX-transduced Autologous Dendritic Cells, NCI Thesaurus)
A class of viral vaccines based on adenovirus genome which was engineered to harbor gene of therapeutic interest, and were to be used in vaccination against cancers.
(Adenovirus Vaccine, NCI Thesaurus)
A cancer vaccine composed of a genetically engineered, replication-deficient type 5 adenovirus carrying the human prostate-specific antigen (PSA), with potential immunostimulating and antineoplastic activities.
(Adenovirus-PSA Prostate Cancer Vaccine, NCI Thesaurus)
Vaccines using pieces of the Melanoma Antigen Recognized by T cells 1 are being studied for their ability to boost the immune response to cancer cells in patients with melanoma.
(Melanoma Antigen Recognized by T cells 1, NCI Dictionary)
A cell-based cancer vaccine consisting of autologous dendritic cells (DCs) pulsed with mesothelioma tumor lysate with potential immunostimulating and antineoplastic activities.
(Mesothelioma Tumor Lysate-Pulsed Autologous Dendritic Cell Vaccine, NCI Thesaurus)
A polysaccharide vaccine used to prevent contraction of meningococcal meningitis.
(Meningococcal Polysaccharide Vaccine MPSV4, NCI Thesaurus)
A cancer vaccine consisting of a proprietary, recombinant modified vaccinia Ankara (MVA) viral vector encoding an epitope of human epidermal growth factor receptor 2 (HER2) with potential antineoplastic activity.
(Modified Vaccinia Ankara (Bavarian Nordic)-HER2 Vaccine, NCI Thesaurus)
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