/ English Dictionary

ZIPPER

Pronunciation (US):

(GB):

 I. (noun) 

Sense 1

Meaning:

A fastener for locking together two toothed edges by means of a sliding tab

Synonyms:

slide fastener; zip; zip fastener; zipper

Classified under:

Nouns denoting man-made objects

Hypernyms ("zipper" is a kind of...):

fastener; fastening; fixing; holdfast (restraint that attaches to something or holds something in place)

Holonyms ("zipper" is a part of...):

cardigan (knitted jacket that is fastened up the front with buttons or a zipper)

dress; frock (a one-piece garment for a woman; has skirt and bodice)

skirt (a garment hanging from the waist; worn mainly by girls and women)

pair of trousers; pant; trousers ((usually in the plural) a garment extending from the waist to the knee or ankle, covering each leg separately)

Derivation:

zip; zipper (close with a zipper)

 II. (verb) 

Sense 1

Meaning:

Close with a zipper

Example:

Zip up your jacket--it's cold

Synonyms:

zip; zip up; zipper

Classified under:

Verbs of touching, hitting, tying, digging

Hypernyms (to "zipper" is one way to...):

fasten; fix; secure (cause to be firmly attached)

Sentence frame:

Somebody ----s something

Derivation:

zipper (a fastener for locking together two toothed edges by means of a sliding tab)

Credits

 Context examples: 

Bipartite DNA binding domain containing a homeo domain and a leucine zipper.

(HD-ZIP Domain, NCI Thesaurus)

The C-terminal leucine zipper and ribosomal S14 motif are not conserved in plant and nematode proteins.

(Neuroblastoma-Amplified Sequence, NCI Thesaurus)

Listeria, Staphylococcus, Streptococcus, and Yersinia are examples of bacteria that enter using the zipper model.

(Bacterial Invasion of Epithelial Cell Pathway, NCI Thesaurus/KEGG)

An orally available inhibitor of maternal embryonic leucine zipper kinase (MELK) with potential antineoplastic activity.

(MELK Inhibitor OTS167, NCI Thesaurus)

Dimerization via leucine zippers of MYC proteins with bHLH/lz proteins, such as MAX, is required for efficient DNA binding.

(MYC Family Gene, NCI Thesaurus)

This protein is comprised of all but the last 4 amino acids of the phosphatidylinositol-binding clathrin assembly protein fused to the C-terminal leucine zipper domain of protein AF-10.

(PICALM/MLLT10 Fusion Protein, NCI Thesaurus)

Sulforaphane activates the transcription factor NF-E2-related factor 2 (Nrf2), a member of the basic leucine zipper family, which binds to and activates antioxidant-response elements (AREs).

(Broccoli sprout extract, NCI Thesaurus)

This protein is comprised of the transactivation domain of the RNA-binding protein EWS followed by the DNA-binding basic domain and leucine zipper dimerization domain of the cyclic AMP-dependent transcription factor ATF-1 protein.

(EWSR1/ATF1 Fusion Protein, NCI Thesaurus)

Many genetic regulatory DNA binding proteins bind to double- or single-stranded DNA in a sequence-specific manner and share common structural motifs such as the zinc-finger, helix-turn-helix, and leucine zipper.

(DNA Binding Protein, NCI Thesaurus)

An N-terminal leucine zipper mediates dimerization of H4 protein and this dimerization is essential to transforming activity.

(D10S170 Protein, NCI Thesaurus)

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